Liver Transplantation for Hepatoblastoma The American Experience

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Liver transplantation for hepatoblastoma. The American experience.

The current role of liver transplantation in treating malignant tumors of the liver is uncertain, except for select histologic types. Pooled data on the results of liver transplantation in 12 children with hepatoblastoma is presented here. One half of the children are alive 24 to 70 (44 +/- 19) months after transplantation with no evidence of recurrence. Three patients (25%) died of tumor recur...

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Pediatric liver transplantation for hepatoblastoma.

Hepatoblastoma is the most common pediatric liver tumor and is usually diagnosed before five years of age. Treatment consists of a combination of chemotherapy and surgery, with the goal being attainment of complete local control by surgical resection and eradication of any extrahepatic disease. Neoadjuvant chemotherapy is utilized and is often beneficial in rendering tumors resectable; however,...

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LIVING-RELATED LIVER TRANSPLANTATION IN CHILDREN: THE SHIRAZ EXPERIENCE

The liver transplantation program was established at Shiraz Nemazee Hospital in 1993. Shortage of cadaver organ supply due to various social and legal issues urged us to develop a living-related liver transplantation (LRLT) program. So far 7 (6 males, 1 female) living-related liver transplantations have been performed at this center. The mean age of patients was 8.21 years (+/- 4.16), with ...

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Treatment of hepatoblastoma: the North American cooperative group experience.

In North America, children with malignant liver tumors have been treated in a cooperative group study since early 1970s. This manuscript describes the results of these studies.

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Liver transplantation in the management of unresectable hepatoblastoma in children.

Complete surgical resection is essential to long-term survival in children with hepatoblastoma. We present the guidelines from the Children's Oncology Group (COG), liver tumor study group of the Societe Internationale Oncologie Pediatrique (SIOPEL), and German Pediatric Oncology Group (GPOH) for early referral of children with potentially unresectable hepatoblastoma to a specialty center with e...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1991

ISSN: 0003-4932

DOI: 10.1097/00000658-199102000-00004